Zinc finger and BTB domain-containing protein 44 (ZBTB44)
Homo sapiens — UniProt Q8NCP5
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger and BTB domain-containing protein 44 (ZBTB44) is a protein from Homo sapiens identified by UniProt accession Q8NCP5, 570 residues long. MolForge cross-references it against 0 known binders and 39 disease associations.
- UniProt accession: Q8NCP5; gene symbol ZBTB44.
- Organism: Homo sapiens.
- Length: 570 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, mean reticulocyte volume and pulse pressure measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger and BTB domain-containing protein 44 |
|---|---|
| UniProt accession | Q8NCP5 |
| Gene | ZBTB44 |
| Organism | Homo sapiens |
| Length | 570 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (39)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.51
- mean reticulocyte volume · score 0.19
- pulse pressure measurement · score 0.06
- hypoparathyroidism, familial isolated, 2 · score 0.05
- systolic blood pressure · score 0.05
- pseudohypoparathyroidism type 2 · score 0.05
- Familial isolated hypoparathyroidism · score 0.04
- diastolic blood pressure · score 0.04
- visual perception measurement · score 0.03
- familial isolated hypoparathyroidism due to agenesis of parathyroid gland · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NCP5-F1 | alphafold | PREDICTED | 54.81 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NCP5.
Amino-acid sequence (570 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZBTB44?
The strongest Open Targets associations for ZBTB44 are neurodegenerative disease, mean reticulocyte volume, pulse pressure measurement, hypoparathyroidism, familial isolated, 2 and systolic blood pressure.
How long is the ZBTB44 protein?
The Homo sapiens ZBTB44 protein (UniProt Q8NCP5) is 570 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NCP5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NCP5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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