F-box only protein 15 (FBXO15)
Homo sapiens — UniProt Q8NCQ5
Data last refreshed: (UniProt release unknown)
Key facts
F-box only protein 15 (FBXO15) is a protein from Homo sapiens identified by UniProt accession Q8NCQ5, 510 residues long. MolForge cross-references it against 0 known binders and 116 disease associations.
- UniProt accession: Q8NCQ5; gene symbol FBXO15.
- Organism: Homo sapiens.
- Length: 510 amino acids.
- Top disease associations (Open Targets): sleep measurement, testosterone measurement and clear cell renal carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | F-box only protein 15 |
|---|---|
| UniProt accession | Q8NCQ5 |
| Gene | FBXO15 |
| Organism | Homo sapiens |
| Length | 510 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (116)
Diseases linked to this target (Open Targets).
- sleep measurement · score 0.25
- testosterone measurement · score 0.21
- clear cell renal carcinoma · score 0.18
- longevity · score 0.15
- 17-hydroxyprogesterone measurement · score 0.14
- PHF-tau measurement · score 0.13
- metabolite measurement · score 0.06
- neutrophil immunodeficiency syndrome · score 0.05
- Blackfan-Diamond anemia · score 0.05
- hereditary neutrophilia · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NCQ5-F1 | alphafold | PREDICTED | 76.64 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NCQ5.
Amino-acid sequence (510 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FBXO15?
The strongest Open Targets associations for FBXO15 are sleep measurement, testosterone measurement, clear cell renal carcinoma, longevity and 17-hydroxyprogesterone measurement.
How long is the FBXO15 protein?
The Homo sapiens FBXO15 protein (UniProt Q8NCQ5) is 510 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NCQ5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NCQ5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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