Protein PROCA1 (PROCA1)
Homo sapiens — UniProt Q8NCQ7
Data last refreshed: (UniProt release unknown)
Key facts
Protein PROCA1 (PROCA1) is a protein from Homo sapiens identified by UniProt accession Q8NCQ7, 364 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.
- UniProt accession: Q8NCQ7; gene symbol PROCA1.
- Organism: Homo sapiens.
- Length: 364 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, urate measurement and mean platelet volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein PROCA1 |
|---|---|
| UniProt accession | Q8NCQ7 |
| Gene | PROCA1 |
| Organism | Homo sapiens |
| Length | 364 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (26)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.21
- urate measurement · score 0.11
- mean platelet volume · score 0.11
- platelet count · score 0.11
- reticulocyte count · score 0.10
- lung adenocarcinoma · score 0.08
- apolipoprotein B measurement · score 0.06
- body height · score 0.06
- pulse pressure measurement · score 0.06
- mean corpuscular volume · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NCQ7-F1 | alphafold | PREDICTED | 45.87 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NCQ7.
Amino-acid sequence (364 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PROCA1?
The strongest Open Targets associations for PROCA1 are neurodegenerative disease, urate measurement, mean platelet volume, platelet count and reticulocyte count.
How long is the PROCA1 protein?
The Homo sapiens PROCA1 protein (UniProt Q8NCQ7) is 364 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NCQ7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NCQ7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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