Sperm microtubule inner protein 6 (SPMIP6)
Homo sapiens — UniProt Q8NCR6
Data last refreshed: (UniProt release unknown)
Key facts
Sperm microtubule inner protein 6 (SPMIP6) is a protein from Homo sapiens identified by UniProt accession Q8NCR6, 262 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.
- UniProt accession: Q8NCR6; gene symbol SPMIP6.
- Organism: Homo sapiens.
- Length: 262 amino acids.
- Top disease associations (Open Targets): body height, Red cell distribution width and diet measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Sperm microtubule inner protein 6 |
|---|---|
| UniProt accession | Q8NCR6 |
| Gene | SPMIP6 |
| Organism | Homo sapiens |
| Length | 262 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (30)
Diseases linked to this target (Open Targets).
- body height · score 0.26
- Red cell distribution width · score 0.21
- diet measurement · score 0.16
- pulse pressure measurement · score 0.10
- heart failure · score 0.05
- hypertension · score 0.05
- astrocytoma · score 0.03
- Crohn's disease · score 0.02
- Immature Reticulocyte Fraction Measurement · score 0.02
- nasopharyngeal neoplasm · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NCR6-F1 | alphafold | PREDICTED | 53.73 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NCR6.
Amino-acid sequence (262 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SPMIP6?
The strongest Open Targets associations for SPMIP6 are body height, Red cell distribution width, diet measurement, pulse pressure measurement and heart failure.
How long is the SPMIP6 protein?
The Homo sapiens SPMIP6 protein (UniProt Q8NCR6) is 262 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NCR6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NCR6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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