Clarin-3 (CLRN3)
Homo sapiens — UniProt Q8NCR9
Data last refreshed: (UniProt release unknown)
Key facts
Clarin-3 (CLRN3) is a protein from Homo sapiens identified by UniProt accession Q8NCR9, 226 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.
- UniProt accession: Q8NCR9; gene symbol CLRN3.
- Organism: Homo sapiens.
- Length: 226 amino acids.
- Top disease associations (Open Targets): PHF-tau measurement, Barrett's esophagus and esophageal adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Clarin-3 |
|---|---|
| UniProt accession | Q8NCR9 |
| Gene | CLRN3 |
| Organism | Homo sapiens |
| Length | 226 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (20)
Diseases linked to this target (Open Targets).
- PHF-tau measurement · score 0.24
- Barrett's esophagus · score 0.09
- esophageal adenocarcinoma · score 0.06
- metabolite measurement · score 0.04
- mean corpuscular volume · score 0.02
- Kidney Oncocytoma · score 0.02
- chromophobe renal cell carcinoma · score 0.02
- IGA glomerulonephritis · score 0.01
- colorectal cancer · score 0.01
- hepatocellular carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NCR9-F1 | alphafold | PREDICTED | 86.55 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NCR9.
Amino-acid sequence (226 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CLRN3?
The strongest Open Targets associations for CLRN3 are PHF-tau measurement, Barrett's esophagus, esophageal adenocarcinoma, metabolite measurement and mean corpuscular volume.
How long is the CLRN3 protein?
The Homo sapiens CLRN3 protein (UniProt Q8NCR9) is 226 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NCR9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NCR9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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