Transmembrane protein 35B (TMEM35B)
Homo sapiens — UniProt Q8NCS4
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane protein 35B (TMEM35B) is a protein from Homo sapiens identified by UniProt accession Q8NCS4, 154 residues long. MolForge cross-references it against 0 known binders and 2 disease associations.
- UniProt accession: Q8NCS4; gene symbol TMEM35B.
- Organism: Homo sapiens.
- Length: 154 amino acids.
- Top disease associations (Open Targets): sitting height measurement and cigarettes per day measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane protein 35B |
|---|---|
| UniProt accession | Q8NCS4 |
| Gene | TMEM35B |
| Organism | Homo sapiens |
| Length | 154 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (2)
Diseases linked to this target (Open Targets).
- sitting height measurement · score 0.08
- cigarettes per day measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NCS4-F1 | alphafold | PREDICTED | 78.85 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NCS4.
Amino-acid sequence (154 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMEM35B?
The strongest Open Targets associations for TMEM35B are sitting height measurement and cigarettes per day measurement.
How long is the TMEM35B protein?
The Homo sapiens TMEM35B protein (UniProt Q8NCS4) is 154 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NCS4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NCS4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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