Choline transporter-like protein 5 (SLC44A5)
Homo sapiens — UniProt Q8NCS7
Data last refreshed: (UniProt release unknown)
Key facts
Choline transporter-like protein 5 (SLC44A5) is a protein from Homo sapiens identified by UniProt accession Q8NCS7, 719 residues long. MolForge cross-references it against 0 known binders and 80 disease associations.
- UniProt accession: Q8NCS7; gene symbol SLC44A5.
- Organism: Homo sapiens.
- Length: 719 amino acids.
- Target class: Transporter.
- Top disease associations (Open Targets): brain volume measurement, serum metabolite measurement and blood protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Choline transporter-like protein 5 |
|---|---|
| UniProt accession | Q8NCS7 |
| Gene | SLC44A5 |
| Organism | Homo sapiens |
| Length | 719 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Transporter (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (80)
Diseases linked to this target (Open Targets).
- brain volume measurement · score 0.44
- serum metabolite measurement · score 0.32
- blood protein measurement · score 0.23
- neurodegenerative disease · score 0.19
- glioblastoma multiforme · score 0.18
- breast adenocarcinoma · score 0.18
- wheezing · score 0.15
- cutaneous melanoma · score 0.14
- facial morphology measurement · score 0.09
- Blackfan-Diamond anemia · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NCS7-F1 | alphafold | PREDICTED | 82.23 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NCS7.
Amino-acid sequence (719 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC44A5?
The strongest Open Targets associations for SLC44A5 are brain volume measurement, serum metabolite measurement, blood protein measurement, neurodegenerative disease and glioblastoma multiforme.
How long is the SLC44A5 protein?
The Homo sapiens SLC44A5 protein (UniProt Q8NCS7) is 719 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NCS7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NCS7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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