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Uncharacterized protein CCDC197 (CCDC197)

Homo sapiens — UniProt Q8NCU1

Gene: CCDC197Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Uncharacterized protein CCDC197 (CCDC197) is a protein from Homo sapiens identified by UniProt accession Q8NCU1, 143 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.

  • UniProt accession: Q8NCU1; gene symbol CCDC197.
  • Organism: Homo sapiens.
  • Length: 143 amino acids.
  • Top disease associations (Open Targets): pulse pressure measurement, aortic measurement and aspartate aminotransferase measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameUncharacterized protein CCDC197
UniProt accessionQ8NCU1
GeneCCDC197
OrganismHomo sapiens
Length143 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (13)

Diseases linked to this target (Open Targets).

  • pulse pressure measurement · score 0.38
  • aortic measurement · score 0.30
  • aspartate aminotransferase measurement · score 0.26
  • systolic blood pressure · score 0.22
  • eosinophil percentage of leukocytes · score 0.12
  • eosinophil count · score 0.09
  • drug use measurement · score 0.04
  • FEV/FVC ratio · score 0.03
  • emphysema · score 0.02
  • monocyte count · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8NCU1-F1alphafoldPREDICTED83.98—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NCU1.

Amino-acid sequence (143 residues)

MAAMDTGQRA DPSNPGDKEG DLQGLWQELY QLQAKQKKLK REVEKHKLFE DYLIKVLEKI PEGCTGWEEP EEVLVEATVK HYGKLFTASQ DTQKRLEAFC QMIQAVHRSL ESLEEDHRAL IASRSGCVSC RRSATASRSS GGS

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with CCDC197?

The strongest Open Targets associations for CCDC197 are pulse pressure measurement, aortic measurement, aspartate aminotransferase measurement, systolic blood pressure and eosinophil percentage of leukocytes.

How long is the CCDC197 protein?

The Homo sapiens CCDC197 protein (UniProt Q8NCU1) is 143 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ8NCU1
GeneCCDC197
OrganismHomo sapiens
Length143
Binders0
Diseases13
View on UniProt