Coiled-coil domain-containing protein 191 (CCDC191)
Homo sapiens — UniProt Q8NCU4
Data last refreshed: (UniProt release unknown)
Key facts
Coiled-coil domain-containing protein 191 (CCDC191) is a protein from Homo sapiens identified by UniProt accession Q8NCU4, 936 residues long. MolForge cross-references it against 0 known binders and 74 disease associations.
- UniProt accession: Q8NCU4; gene symbol CCDC191.
- Organism: Homo sapiens.
- Length: 936 amino acids.
- Top disease associations (Open Targets): HIV infection, azoospermia and male infertility with teratozoospermia due to single gene mutation.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Coiled-coil domain-containing protein 191 |
|---|---|
| UniProt accession | Q8NCU4 |
| Gene | CCDC191 |
| Organism | Homo sapiens |
| Length | 936 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (74)
Diseases linked to this target (Open Targets).
- HIV infection · score 0.15
- azoospermia · score 0.07
- male infertility with teratozoospermia due to single gene mutation · score 0.05
- partial chromosome Y deletion · score 0.05
- Male infertility with spermatogenesis disorder due to single gene mutation · score 0.05
- Adie syndrome · score 0.05
- spermatogenic failure 61 · score 0.05
- spermatogenic failure 55 · score 0.05
- spermatogenic failure 3 · score 0.05
- spermatogenic failure 59 · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NCU4-F1 | alphafold | PREDICTED | 70.91 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NCU4.
Amino-acid sequence (936 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CCDC191?
The strongest Open Targets associations for CCDC191 are HIV infection, azoospermia, male infertility with teratozoospermia due to single gene mutation, partial chromosome Y deletion and Male infertility with spermatogenesis disorder due to single gene mutation.
How long is the CCDC191 protein?
The Homo sapiens CCDC191 protein (UniProt Q8NCU4) is 936 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NCU4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NCU4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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