C2 calcium-dependent domain-containing protein 4A (C2CD4A)
Homo sapiens — UniProt Q8NCU7
Data last refreshed: (UniProt release unknown)
Key facts
C2 calcium-dependent domain-containing protein 4A (C2CD4A) is a protein from Homo sapiens identified by UniProt accession Q8NCU7, 369 residues long. MolForge cross-references it against 0 known binders and 98 disease associations.
- UniProt accession: Q8NCU7; gene symbol C2CD4A.
- Organism: Homo sapiens.
- Length: 369 amino acids.
- Top disease associations (Open Targets): IGF-1 measurement, type 2 diabetes mellitus and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | C2 calcium-dependent domain-containing protein 4A |
|---|---|
| UniProt accession | Q8NCU7 |
| Gene | C2CD4A |
| Organism | Homo sapiens |
| Length | 369 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (98)
Diseases linked to this target (Open Targets).
- IGF-1 measurement · score 0.53
- type 2 diabetes mellitus · score 0.47
- body height · score 0.42
- fasting blood glucose measurement · score 0.41
- insulin measurement · score 0.40
- lean body mass · score 0.40
- BMI-adjusted fasting blood glucose measurement · score 0.37
- Drugs used in diabetes use measurement · score 0.37
- body mass index · score 0.37
- glucose measurement · score 0.35
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NCU7-F1 | alphafold | PREDICTED | 58.87 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NCU7.
Amino-acid sequence (369 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C2CD4A?
The strongest Open Targets associations for C2CD4A are IGF-1 measurement, type 2 diabetes mellitus, body height, fasting blood glucose measurement and insulin measurement.
How long is the C2CD4A protein?
The Homo sapiens C2CD4A protein (UniProt Q8NCU7) is 369 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NCU7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NCU7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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