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Coiled-coil domain-containing protein 150 (CCDC150)

Homo sapiens — UniProt Q8NCX0

Gene: CCDC150Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Coiled-coil domain-containing protein 150 (CCDC150) is a protein from Homo sapiens identified by UniProt accession Q8NCX0, 1101 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.

  • UniProt accession: Q8NCX0; gene symbol CCDC150.
  • Organism: Homo sapiens.
  • Length: 1101 amino acids.
  • Top disease associations (Open Targets): lymphocyte count, response to vaccine and triple-negative breast cancer.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameCoiled-coil domain-containing protein 150
UniProt accessionQ8NCX0
GeneCCDC150
OrganismHomo sapiens
Length1101 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (16)

Diseases linked to this target (Open Targets).

  • lymphocyte count · score 0.14
  • response to vaccine · score 0.14
  • triple-negative breast cancer · score 0.07
  • neoplasm · score 0.05
  • chronotype measurement · score 0.04
  • BMI-adjusted waist-hip ratio · score 0.03
  • arterial stiffness measurement · score 0.03
  • non-small cell lung carcinoma · score 0.02
  • blood phosphate measurement · score 0.02
  • heel bone mineral density · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8NCX0-F1alphafoldPREDICTED74.19—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NCX0.

Amino-acid sequence (1101 residues)

MDCKVHMETT VSRPVLSPTH INATASETFT VLQQRMRIVE EQTSSLRDDL IMLDFGEKRG YLEAPDCLED LDSQKVISPI QNEAICAGKT DILWKNCEFL VNRMCRLESL MQSLKMNIFR LQTEKDLNPQ KTAFLKDRLN AIQEEHSKDL KLLHLEVMNL RQQLRAVKEE EDKAQDEVQR LTATLKIASQ TKKNAAIIEE ELKTTKRKMN LKIQELRRQL AQEKYLRESL EKSASAMLLK IQEMGSTVEV ERKQVHILQQ NCIALRDSIQ SAQELLAQEQ KKKEELEIAT SQLKSDLTSR DDLISKLVEE NKNLQISFNK EHEENAYLRS EIMSLHEASE KAQVLNDQLT KKCSELSCML QTVTMEKARI IADHQAILQV EQKMMTQTFQ EQNLLLDAAH ASITNELQTV QNEKTQLQAH LDHLILEHNQ CIQKAQDAEK RTAVQKELLE STIARLRGEL EASMQEKKSL LEEKERFQRE VNKTEKEIVQ ERCNLEKELA KNKVDINTLT HNLQTLEEEN KHLADQMASL ELQQVTSDYH GLAQQKVEKI TESKNKLAYE NGKLQIKVKQ LEEQVQSFTD TSLQNDHLRK MNKYLQTKYA QANSELSAKR VHLQQADAHL KEVKSILERS KEELSRTVKC RNAALKESQK LKEDLEAVED RENKKVGNFQ RQLAEAKEDN CKVTIMLENV LASHSKMQGA LEKVQIELGR RDSEIAGLKK ERDLNQQRVQ KLEAEVDQWQ ARMLVMEDQH NSEIESLQKA LGVAREDNRK LAMSLEQALQ TNNHLQTKLD HIQEQLESKE LERQNLETFK DRMTEESKVE AELHAERIEA LRKQFQTERE TTKKVAQREV AELKKALDEA NFRSVEVSRT NRELRQKLAE LEKILESNKE KIKNQKTQIK LHLSAKANNA QNIERMKQIE KELKQMELIK DQYQKKNYEQ SLSIQRFVCE MTNLQKEMQM LAKSQYDASV RNKQQELHLE AERKIRQELE NRCQELEETV RHLKKCKEAT ENTLKEASVE SEQITANLEE AHRWFKHRFD GLQLELTKNR LQRPSGEDRW QEKDQDVKHD VMSNQSVLHR WERKQNLRPM PKKYHSEVQR K

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with CCDC150?

The strongest Open Targets associations for CCDC150 are lymphocyte count, response to vaccine, triple-negative breast cancer, neoplasm and chronotype measurement.

How long is the CCDC150 protein?

The Homo sapiens CCDC150 protein (UniProt Q8NCX0) is 1101 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ8NCX0
GeneCCDC150
OrganismHomo sapiens
Length1101
Binders0
Diseases16
View on UniProt