Myb/SANT-like DNA-binding domain-containing protein 4 (MSANTD4)
Homo sapiens — UniProt Q8NCY6
Data last refreshed: (UniProt release unknown)
Key facts
Myb/SANT-like DNA-binding domain-containing protein 4 (MSANTD4) is a protein from Homo sapiens identified by UniProt accession Q8NCY6, 345 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.
- UniProt accession: Q8NCY6; gene symbol MSANTD4.
- Organism: Homo sapiens.
- Length: 345 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, age at first sexual intercourse measurement and mathematical ability.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Myb/SANT-like DNA-binding domain-containing protein 4 |
|---|---|
| UniProt accession | Q8NCY6 |
| Gene | MSANTD4 |
| Organism | Homo sapiens |
| Length | 345 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (24)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.51
- age at first sexual intercourse measurement · score 0.27
- mathematical ability · score 0.25
- self reported educational attainment · score 0.22
- antisocial behaviour measurement · score 0.16
- substance abuse · score 0.16
- attention deficit hyperactivity disorder · score 0.16
- cognitive function measurement · score 0.15
- intelligence · score 0.14
- protein measurement · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NCY6-F1 | alphafold | PREDICTED | 69.31 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NCY6.
Amino-acid sequence (345 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MSANTD4?
The strongest Open Targets associations for MSANTD4 are neurodegenerative disease, age at first sexual intercourse measurement, mathematical ability, self reported educational attainment and antisocial behaviour measurement.
How long is the MSANTD4 protein?
The Homo sapiens MSANTD4 protein (UniProt Q8NCY6) is 345 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NCY6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NCY6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.