Protein LSM14 homolog A (LSM14A)
Homo sapiens — UniProt Q8ND56
Data last refreshed: (UniProt release unknown)
Key facts
Protein LSM14 homolog A (LSM14A) is a protein from Homo sapiens identified by UniProt accession Q8ND56, 463 residues long. MolForge cross-references it against 0 known binders and 156 disease associations.
- UniProt accession: Q8ND56; gene symbol LSM14A.
- Organism: Homo sapiens.
- Length: 463 amino acids.
- Top disease associations (Open Targets): mean corpuscular hemoglobin concentration, Red cell distribution width and reticulocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein LSM14 homolog A |
|---|---|
| UniProt accession | Q8ND56 |
| Gene | LSM14A |
| Organism | Homo sapiens |
| Length | 463 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (156)
Diseases linked to this target (Open Targets).
- mean corpuscular hemoglobin concentration · score 0.36
- Red cell distribution width · score 0.32
- reticulocyte count · score 0.28
- mean corpuscular hemoglobin · score 0.27
- sitting height measurement · score 0.26
- IGF-1 measurement · score 0.26
- reticulocyte measurement · score 0.22
- neurodegenerative disease · score 0.22
- insulin like growth factor measurement · score 0.21
- hepatocellular carcinoma · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8ND56-F1 | alphafold | PREDICTED | 59.16 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8ND56.
Amino-acid sequence (463 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LSM14A?
The strongest Open Targets associations for LSM14A are mean corpuscular hemoglobin concentration, Red cell distribution width, reticulocyte count, mean corpuscular hemoglobin and sitting height measurement.
How long is the LSM14A protein?
The Homo sapiens LSM14A protein (UniProt Q8ND56) is 463 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8ND56 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8ND56 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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