40S small subunit processome assembly factor 1 (FSAF1)

About 40S small subunit processome assembly factor 1

40S small subunit processome assembly factor 1 (FSAF1) is a protein from Homo sapiens identified by UniProt accession Q8NDD1, 293 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.

Target properties

Protein name	40S small subunit processome assembly factor 1
UniProt accession	Q8NDD1
Gene	FSAF1
Organism	Homo sapiens
Length	293 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (7)

Diseases linked to this target (Open Targets).

lung adenocarcinoma · score 0.02
ovarian carcinoma · score 0.01
cancer · score 0.00
neoplasm · score 0.00
type 1 diabetes mellitus · score 0.00
non-small cell lung carcinoma · score 0.00
hepatocellular carcinoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NDD1-F1	alphafold	PREDICTED	68.06	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NDD1.

Amino-acid sequence (293 residues)

MRVDSSADPT MSQEQGPGSS TPPSSPTLLD ALLQNLYDFG GTEGETEQKK IIKKRENKKR DVMASAALAA EPSPLPGSLI RGQRKSASSF FKELREERHC APSGTPTGPE ILAAAVPPSS LKNNREQVEV VEFHSNKKRK LTPDHNKNTK QANPSVLERD VDTQEFNLEK ARLEVHRFGI TGYGKGKERI LEQERAIMLG AKPPKKSYVN YKVLQEQIKE KKAAKEEEKR LAQETDIFKK KKRKGQEDRK SKKKSAPSIL SNGRIGQVGK FKNGTLILSP VDIKKINSSR VAK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards