EH domain-binding protein 1 (EHBP1)
Homo sapiens — UniProt Q8NDI1
Data last refreshed: (UniProt release unknown)
Key facts
EH domain-binding protein 1 (EHBP1) is a protein from Homo sapiens identified by UniProt accession Q8NDI1, 1231 residues long. MolForge cross-references it against 0 known binders and 81 disease associations.
- UniProt accession: Q8NDI1; gene symbol EHBP1.
- Organism: Homo sapiens.
- Length: 1231 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, low density lipoprotein cholesterol measurement and body mass index.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | EH domain-binding protein 1 |
|---|---|
| UniProt accession | Q8NDI1 |
| Gene | EHBP1 |
| Organism | Homo sapiens |
| Length | 1231 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (81)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.49
- low density lipoprotein cholesterol measurement · score 0.39
- body mass index · score 0.37
- mathematical ability · score 0.34
- alcohol consumption measurement · score 0.33
- Familial prostate cancer · score 0.33
- total cholesterol measurement · score 0.32
- apolipoprotein B measurement · score 0.31
- alcohol drinking · score 0.30
- HMG CoA reductase inhibitor use measurement · score 0.29
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NDI1-F1 | alphafold | PREDICTED | 57.48 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NDI1.
Amino-acid sequence (1231 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with EHBP1?
The strongest Open Targets associations for EHBP1 are neurodegenerative disease, low density lipoprotein cholesterol measurement, body mass index, mathematical ability and alcohol consumption measurement.
How long is the EHBP1 protein?
The Homo sapiens EHBP1 protein (UniProt Q8NDI1) is 1231 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NDI1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NDI1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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