Zinc finger protein 540 (ZNF540)
Homo sapiens — UniProt Q8NDQ6
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 540 (ZNF540) is a protein from Homo sapiens identified by UniProt accession Q8NDQ6, 660 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.
- UniProt accession: Q8NDQ6; gene symbol ZNF540.
- Organism: Homo sapiens.
- Length: 660 amino acids.
- Top disease associations (Open Targets): sex hormone-binding globulin measurement, neurodegenerative disease and glomerular filtration rate.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 540 |
|---|---|
| UniProt accession | Q8NDQ6 |
| Gene | ZNF540 |
| Organism | Homo sapiens |
| Length | 660 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (29)
Diseases linked to this target (Open Targets).
- sex hormone-binding globulin measurement · score 0.17
- neurodegenerative disease · score 0.15
- glomerular filtration rate · score 0.14
- genetic disorder · score 0.12
- FEV/FVC ratio · score 0.11
- cystatin C measurement · score 0.08
- creatinine measurement · score 0.08
- C-reactive protein measurement · score 0.05
- Abnormality of refraction · score 0.04
- serum urea measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NDQ6-F1 | alphafold | PREDICTED | 75.03 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NDQ6.
Amino-acid sequence (660 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF540?
The strongest Open Targets associations for ZNF540 are sex hormone-binding globulin measurement, neurodegenerative disease, glomerular filtration rate, genetic disorder and FEV/FVC ratio.
How long is the ZNF540 protein?
The Homo sapiens ZNF540 protein (UniProt Q8NDQ6) is 660 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NDQ6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NDQ6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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