Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 (ST6GALNAC3)
Homo sapiens — UniProt Q8NDV1
Data last refreshed: (UniProt release unknown)
Key facts
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 (ST6GALNAC3) is a protein from Homo sapiens identified by UniProt accession Q8NDV1, 305 residues long. MolForge cross-references it against 0 known binders and 83 disease associations.
- UniProt accession: Q8NDV1; gene symbol ST6GALNAC3.
- Organism: Homo sapiens.
- Length: 305 amino acids.
- Top disease associations (Open Targets): COVID-19, smoking status measurement and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 |
|---|---|
| UniProt accession | Q8NDV1 |
| Gene | ST6GALNAC3 |
| Organism | Homo sapiens |
| Length | 305 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (83)
Diseases linked to this target (Open Targets).
- COVID-19 · score 0.46
- smoking status measurement · score 0.39
- body height · score 0.37
- severe acute respiratory syndrome · score 0.37
- heel bone mineral density · score 0.34
- childhood trauma measurement · score 0.31
- adolescent idiopathic scoliosis · score 0.31
- blood protein measurement · score 0.29
- glioblastoma multiforme · score 0.19
- lung adenocarcinoma · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NDV1-F1 | alphafold | PREDICTED | 89.13 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NDV1.
Amino-acid sequence (305 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ST6GALNAC3?
The strongest Open Targets associations for ST6GALNAC3 are COVID-19, smoking status measurement, body height, severe acute respiratory syndrome and heel bone mineral density.
How long is the ST6GALNAC3 protein?
The Homo sapiens ST6GALNAC3 protein (UniProt Q8NDV1) is 305 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NDV1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NDV1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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