PH and SEC7 domain-containing protein 4 (PSD4)
Homo sapiens — UniProt Q8NDX1
Data last refreshed: (UniProt release unknown)
Key facts
PH and SEC7 domain-containing protein 4 (PSD4) is a protein from Homo sapiens identified by UniProt accession Q8NDX1, 1056 residues long. MolForge cross-references it against 0 known binders and 90 disease associations.
- UniProt accession: Q8NDX1; gene symbol PSD4.
- Organism: Homo sapiens.
- Length: 1056 amino acids.
- Top disease associations (Open Targets): hemoglobin measurement, lymphocyte count and erythrocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | PH and SEC7 domain-containing protein 4 |
|---|---|
| UniProt accession | Q8NDX1 |
| Gene | PSD4 |
| Organism | Homo sapiens |
| Length | 1056 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (90)
Diseases linked to this target (Open Targets).
- hemoglobin measurement · score 0.44
- lymphocyte count · score 0.43
- erythrocyte count · score 0.42
- hematocrit · score 0.42
- lean body mass · score 0.42
- ovarian mucinous adenocarcinoma · score 0.37
- red blood cell density measurement · score 0.37
- leukocyte count · score 0.34
- glomerular filtration rate · score 0.34
- body weight · score 0.34
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NDX1-F1 | alphafold | PREDICTED | 54.84 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NDX1.
Amino-acid sequence (1056 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PSD4?
The strongest Open Targets associations for PSD4 are hemoglobin measurement, lymphocyte count, erythrocyte count, hematocrit and lean body mass.
How long is the PSD4 protein?
The Homo sapiens PSD4 protein (UniProt Q8NDX1) is 1056 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NDX1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NDX1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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