Zinc finger protein 740 (ZNF740)
Homo sapiens — UniProt Q8NDX6
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 740 (ZNF740) is a protein from Homo sapiens identified by UniProt accession Q8NDX6, 193 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.
- UniProt accession: Q8NDX6; gene symbol ZNF740.
- Organism: Homo sapiens.
- Length: 193 amino acids.
- Top disease associations (Open Targets): pancreatic adenocarcinoma, mathematical ability and lymphocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 740 |
|---|---|
| UniProt accession | Q8NDX6 |
| Gene | ZNF740 |
| Organism | Homo sapiens |
| Length | 193 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (15)
Diseases linked to this target (Open Targets).
- pancreatic adenocarcinoma · score 0.14
- mathematical ability · score 0.09
- lymphocyte count · score 0.08
- self reported educational attainment · score 0.07
- type 1 diabetes mellitus · score 0.06
- base metabolic rate measurement · score 0.02
- whole body water mass · score 0.02
- acute myeloid leukemia · score 0.01
- Cholestasis · score 0.01
- ulcerative colitis · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NDX6-F1 | alphafold | PREDICTED | 65.32 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NDX6.
Amino-acid sequence (193 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF740?
The strongest Open Targets associations for ZNF740 are pancreatic adenocarcinoma, mathematical ability, lymphocyte count, self reported educational attainment and type 1 diabetes mellitus.
How long is the ZNF740 protein?
The Homo sapiens ZNF740 protein (UniProt Q8NDX6) is 193 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NDX6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NDX6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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