Lymphocyte antigen 6 complex locus protein G5b (LY6G5B)
Homo sapiens — UniProt Q8NDX9
Data last refreshed: (UniProt release unknown)
Key facts
Lymphocyte antigen 6 complex locus protein G5b (LY6G5B) is a protein from Homo sapiens identified by UniProt accession Q8NDX9, 201 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.
- UniProt accession: Q8NDX9; gene symbol LY6G5B.
- Organism: Homo sapiens.
- Length: 201 amino acids.
- Top disease associations (Open Targets): blood protein measurement, rheumatoid arthritis and sphingolipid measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Lymphocyte antigen 6 complex locus protein G5b |
|---|---|
| UniProt accession | Q8NDX9 |
| Gene | LY6G5B |
| Organism | Homo sapiens |
| Length | 201 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (16)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.24
- rheumatoid arthritis · score 0.12
- sphingolipid measurement · score 0.09
- fasting blood glucose measurement · score 0.09
- telomere length · score 0.05
- body weight · score 0.05
- anthropometric measurement · score 0.05
- glomerulonephritis · score 0.04
- hypertension · score 0.04
- age at menopause · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NDX9-F1 | alphafold | PREDICTED | 75.81 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NDX9.
Amino-acid sequence (201 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LY6G5B?
The strongest Open Targets associations for LY6G5B are blood protein measurement, rheumatoid arthritis, sphingolipid measurement, fasting blood glucose measurement and telomere length.
How long is the LY6G5B protein?
The Homo sapiens LY6G5B protein (UniProt Q8NDX9) is 201 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NDX9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NDX9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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