Divergent protein kinase domain 2A (DIPK2A)
Homo sapiens — UniProt Q8NDZ4
Data last refreshed: (UniProt release unknown)
Key facts
Divergent protein kinase domain 2A (DIPK2A) is a protein from Homo sapiens identified by UniProt accession Q8NDZ4, 430 residues long. MolForge cross-references it against 0 known binders and 29 disease associations.
- UniProt accession: Q8NDZ4; gene symbol DIPK2A.
- Organism: Homo sapiens.
- Length: 430 amino acids.
- Top disease associations (Open Targets): self reported educational attainment, mathematical ability and risk-taking behaviour.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Divergent protein kinase domain 2A |
|---|---|
| UniProt accession | Q8NDZ4 |
| Gene | DIPK2A |
| Organism | Homo sapiens |
| Length | 430 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (29)
Diseases linked to this target (Open Targets).
- self reported educational attainment · score 0.35
- mathematical ability · score 0.34
- risk-taking behaviour · score 0.34
- hemoglobin measurement · score 0.29
- smoking status measurement · score 0.27
- cognitive function measurement · score 0.25
- erythrocyte count · score 0.25
- PHF-tau measurement · score 0.22
- pathological myopia · score 0.19
- neurofibrillary tangles measurement · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NDZ4-F1 | alphafold | PREDICTED | 89.38 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NDZ4.
Amino-acid sequence (430 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DIPK2A?
The strongest Open Targets associations for DIPK2A are self reported educational attainment, mathematical ability, risk-taking behaviour, hemoglobin measurement and smoking status measurement.
How long is the DIPK2A protein?
The Homo sapiens DIPK2A protein (UniProt Q8NDZ4) is 430 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NDZ4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NDZ4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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