F-box only protein 36 (FBXO36)
Homo sapiens — UniProt Q8NEA4
Data last refreshed: (UniProt release unknown)
Key facts
F-box only protein 36 (FBXO36) is a protein from Homo sapiens identified by UniProt accession Q8NEA4, 188 residues long. MolForge cross-references it against 0 known binders and 130 disease associations.
- UniProt accession: Q8NEA4; gene symbol FBXO36.
- Organism: Homo sapiens.
- Length: 188 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, body mass index and body fat percentage.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | F-box only protein 36 |
|---|---|
| UniProt accession | Q8NEA4 |
| Gene | FBXO36 |
| Organism | Homo sapiens |
| Length | 188 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (130)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- body mass index · score 0.21
- body fat percentage · score 0.19
- systolic blood pressure · score 0.18
- vital capacity · score 0.17
- mean arterial pressure · score 0.15
- lean body mass · score 0.15
- body height · score 0.14
- creatinine measurement · score 0.14
- waist circumference · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NEA4-F1 | alphafold | PREDICTED | 89.73 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NEA4.
Amino-acid sequence (188 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FBXO36?
The strongest Open Targets associations for FBXO36 are neurodegenerative disease, body mass index, body fat percentage, systolic blood pressure and vital capacity.
How long is the FBXO36 protein?
The Homo sapiens FBXO36 protein (UniProt Q8NEA4) is 188 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NEA4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NEA4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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