F-box only protein 36 (FBXO36)

About F-box only protein 36

F-box only protein 36 (FBXO36) is a protein from Homo sapiens identified by UniProt accession Q8NEA4, 188 residues long. MolForge cross-references it against 0 known binders and 130 disease associations.

Target properties

Protein name	F-box only protein 36
UniProt accession	Q8NEA4
Gene	FBXO36
Organism	Homo sapiens
Length	188 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (130)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.53
body mass index · score 0.21
body fat percentage · score 0.19
systolic blood pressure · score 0.18
vital capacity · score 0.17
mean arterial pressure · score 0.15
lean body mass · score 0.15
body height · score 0.14
creatinine measurement · score 0.14
waist circumference · score 0.13

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NEA4-F1	alphafold	PREDICTED	89.73	—

Amino-acid sequence (188 residues)

MASWLPETLF ETVGQGPPPS KDYYQLLVTR SQVIFRWWKI SLRSEYRSTK PGEAKETHED FLENSHLQGQ TALIFGARIL DYVINLCKGK FDFLERLSDD LLLTIISYLD LEDIARLCQT SHRFAKLCMS DKLWEQIVQS TCDTITPDVR ALAEDTGWRQ LFFTNKLQLQ RQLRKRKQKY GNLREKQP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards