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Uncharacterized protein C19orf18 (C19orf18)

Homo sapiens — UniProt Q8NEA5

Gene: C19orf18Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Uncharacterized protein C19orf18 (C19orf18) is a protein from Homo sapiens identified by UniProt accession Q8NEA5, 215 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.

  • UniProt accession: Q8NEA5; gene symbol C19orf18.
  • Organism: Homo sapiens.
  • Length: 215 amino acids.
  • Top disease associations (Open Targets): body height, mean corpuscular hemoglobin and mean corpuscular hemoglobin concentration.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameUncharacterized protein C19orf18
UniProt accessionQ8NEA5
GeneC19orf18
OrganismHomo sapiens
Length215 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (9)

Diseases linked to this target (Open Targets).

  • body height · score 0.23
  • mean corpuscular hemoglobin · score 0.09
  • mean corpuscular hemoglobin concentration · score 0.07
  • total cholesterol measurement · score 0.03
  • mean corpuscular volume · score 0.02
  • prostate carcinoma · score 0.01
  • pancreatic adenocarcinoma · score 0.01
  • psoriasis · score 0.00
  • leukemia, acute lymphoblastic, susceptibility to, 3 · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8NEA5-F1alphafoldPREDICTED61.47—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NEA5.

Amino-acid sequence (215 residues)

MDKVQSGFLI LFLFLMECQL HLCLPYADGL HPTGNITGLP GSKRSQPPRN ITKEPKVFFH KTQLPGIQGA ASRSTAASPT NPMKFLRNKA IIRHRPALVK VILISSVAFS IALICGMAIS YMIYRLAQAE ERQQLESLYK NLRIPLLGDE EEGSEDEGES THLLPENENE LEKFIHSVII SKRSKNIKKK LKEEQNSVTE NKTKNASHNG KMEDL

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with C19orf18?

The strongest Open Targets associations for C19orf18 are body height, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, total cholesterol measurement and mean corpuscular volume.

How long is the C19orf18 protein?

The Homo sapiens C19orf18 protein (UniProt Q8NEA5) is 215 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ8NEA5
GeneC19orf18
OrganismHomo sapiens
Length215
Binders0
Diseases9
View on UniProt