Phospholipid phosphatase 5 (PLPP5)
Homo sapiens — UniProt Q8NEB5
Data last refreshed: (UniProt release unknown)
Key facts
Phospholipid phosphatase 5 (PLPP5) is a protein from Homo sapiens identified by UniProt accession Q8NEB5, 264 residues long. MolForge cross-references it against 0 known binders and 50 disease associations.
- UniProt accession: Q8NEB5; gene symbol PLPP5.
- Organism: Homo sapiens.
- Length: 264 amino acids.
- Top disease associations (Open Targets): calcium measurement, breast adenocarcinoma and Immature Reticulocyte Fraction Measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Phospholipid phosphatase 5 |
|---|---|
| UniProt accession | Q8NEB5 |
| Gene | PLPP5 |
| Organism | Homo sapiens |
| Length | 264 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (50)
Diseases linked to this target (Open Targets).
- calcium measurement · score 0.24
- breast adenocarcinoma · score 0.23
- Immature Reticulocyte Fraction Measurement · score 0.22
- Red cell distribution width · score 0.20
- body height · score 0.19
- mean platelet volume · score 0.16
- total blood protein measurement · score 0.14
- urate measurement · score 0.14
- schizophrenia · score 0.13
- lean body mass · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NEB5-F1 | alphafold | PREDICTED | 91.71 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NEB5.
Amino-acid sequence (264 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PLPP5?
The strongest Open Targets associations for PLPP5 are calcium measurement, breast adenocarcinoma, Immature Reticulocyte Fraction Measurement, Red cell distribution width and body height.
How long is the PLPP5 protein?
The Homo sapiens PLPP5 protein (UniProt Q8NEB5) is 264 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NEB5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NEB5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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