Protein FAM83F (FAM83F)
Homo sapiens — UniProt Q8NEG4
Data last refreshed: (UniProt release unknown)
Key facts
Protein FAM83F (FAM83F) is a protein from Homo sapiens identified by UniProt accession Q8NEG4, 500 residues long. MolForge cross-references it against 0 known binders and 32 disease associations.
- UniProt accession: Q8NEG4; gene symbol FAM83F.
- Organism: Homo sapiens.
- Length: 500 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, mean platelet volume and prostate carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein FAM83F |
|---|---|
| UniProt accession | Q8NEG4 |
| Gene | FAM83F |
| Organism | Homo sapiens |
| Length | 500 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (32)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.50
- mean platelet volume · score 0.13
- prostate carcinoma · score 0.13
- azoospermia · score 0.12
- Abnormal sperm morphology · score 0.12
- Reduced sperm motility · score 0.12
- type 2 diabetes mellitus · score 0.10
- papillary thyroid carcinoma · score 0.07
- calf circumference measurement · score 0.07
- metabolite measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NEG4-F1 | alphafold | PREDICTED | 66.99 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NEG4.
Amino-acid sequence (500 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FAM83F?
The strongest Open Targets associations for FAM83F are neurodegenerative disease, mean platelet volume, prostate carcinoma, azoospermia and Abnormal sperm morphology.
How long is the FAM83F protein?
The Homo sapiens FAM83F protein (UniProt Q8NEG4) is 500 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NEG4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NEG4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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