Coiled-coil domain-containing protein 54 (CCDC54)
Homo sapiens — UniProt Q8NEL0
Data last refreshed: (UniProt release unknown)
Key facts
Coiled-coil domain-containing protein 54 (CCDC54) is a protein from Homo sapiens identified by UniProt accession Q8NEL0, 328 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.
- UniProt accession: Q8NEL0; gene symbol CCDC54.
- Organism: Homo sapiens.
- Length: 328 amino acids.
- Top disease associations (Open Targets): neuroticism measurement, prostate carcinoma and brain measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Coiled-coil domain-containing protein 54 |
|---|---|
| UniProt accession | Q8NEL0 |
| Gene | CCDC54 |
| Organism | Homo sapiens |
| Length | 328 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (20)
Diseases linked to this target (Open Targets).
- neuroticism measurement · score 0.30
- prostate carcinoma · score 0.30
- brain measurement · score 0.29
- worry measurement · score 0.29
- electrocardiography · score 0.28
- asthma · score 0.26
- allergic disease · score 0.26
- protein measurement · score 0.17
- neurotic disorder · score 0.06
- calcium measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NEL0-F1 | alphafold | PREDICTED | 59.40 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NEL0.
Amino-acid sequence (328 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CCDC54?
The strongest Open Targets associations for CCDC54 are neuroticism measurement, prostate carcinoma, brain measurement, worry measurement and electrocardiography.
How long is the CCDC54 protein?
The Homo sapiens CCDC54 protein (UniProt Q8NEL0) is 328 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NEL0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NEL0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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