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Transmembrane protein C1orf162 (C1orf162)

Homo sapiens — UniProt Q8NEQ5

Gene: C1orf162Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Transmembrane protein C1orf162 (C1orf162) is a protein from Homo sapiens identified by UniProt accession Q8NEQ5, 155 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.

  • UniProt accession: Q8NEQ5; gene symbol C1orf162.
  • Organism: Homo sapiens.
  • Length: 155 amino acids.
  • Top disease associations (Open Targets): Sepsis, Acute hepatic failure and joint disease.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameTransmembrane protein C1orf162
UniProt accessionQ8NEQ5
GeneC1orf162
OrganismHomo sapiens
Length155 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (30)

Diseases linked to this target (Open Targets).

  • Sepsis · score 0.03
  • Acute hepatic failure · score 0.03
  • joint disease · score 0.03
  • clear cell renal carcinoma · score 0.02
  • lung carcinoma · score 0.02
  • non-small cell lung carcinoma · score 0.02
  • calcium measurement · score 0.02
  • osteosarcoma · score 0.01
  • cutaneous lupus erythematosus · score 0.01
  • rosacea · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8NEQ5-F1alphafoldPREDICTED64.92—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NEQ5.

Amino-acid sequence (155 residues)

MGGNGSTCKP DTERQGTLST AAPTTSPAPC LSNHHNKKHL ILAFCAGVLL TLLLIAFIFL IIKSYRKYRR ERLPISPGPL LRWVPLLSGT MADHSKPQAP DPHSDPPAKL SSIPGESLTY ASTTFKLSEE KSNHLAENHS ADFDPIVYAQ IKVTN

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with C1orf162?

The strongest Open Targets associations for C1orf162 are Sepsis, Acute hepatic failure, joint disease, clear cell renal carcinoma and lung carcinoma.

How long is the C1orf162 protein?

The Homo sapiens C1orf162 protein (UniProt Q8NEQ5) is 155 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ8NEQ5
GeneC1orf162
OrganismHomo sapiens
Length155
Binders0
Diseases30
View on UniProt