Steroid receptor-associated and regulated protein (SRARP)
Homo sapiens — UniProt Q8NEQ6
Data last refreshed: (UniProt release unknown)
Key facts
Steroid receptor-associated and regulated protein (SRARP) is a protein from Homo sapiens identified by UniProt accession Q8NEQ6, 169 residues long. MolForge cross-references it against 0 known binders and 42 disease associations.
- UniProt accession: Q8NEQ6; gene symbol SRARP.
- Organism: Homo sapiens.
- Length: 169 amino acids.
- Top disease associations (Open Targets): sitting height measurement, left ventricular ejection fraction measurement and hypertrophic cardiomyopathy.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Steroid receptor-associated and regulated protein |
|---|---|
| UniProt accession | Q8NEQ6 |
| Gene | SRARP |
| Organism | Homo sapiens |
| Length | 169 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (42)
Diseases linked to this target (Open Targets).
- sitting height measurement · score 0.15
- left ventricular ejection fraction measurement · score 0.12
- hypertrophic cardiomyopathy · score 0.11
- dilated cardiomyopathy · score 0.11
- neoplasm · score 0.09
- heart function measurement · score 0.08
- cancer · score 0.08
- left ventricular systolic function measurement · score 0.08
- creatinine measurement · score 0.07
- glomerular filtration rate · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NEQ6-F1 | alphafold | PREDICTED | 51.79 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NEQ6.
Amino-acid sequence (169 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SRARP?
The strongest Open Targets associations for SRARP are sitting height measurement, left ventricular ejection fraction measurement, hypertrophic cardiomyopathy, dilated cardiomyopathy and neoplasm.
How long is the SRARP protein?
The Homo sapiens SRARP protein (UniProt Q8NEQ6) is 169 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NEQ6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NEQ6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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