Olfactory receptor 4C5 (OR4C5)
Homo sapiens — UniProt Q8NGB2
Data last refreshed: (UniProt release unknown)
Key facts
Olfactory receptor 4C5 (OR4C5) is a protein from Homo sapiens identified by UniProt accession Q8NGB2, 326 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.
- UniProt accession: Q8NGB2; gene symbol OR4C5.
- Organism: Homo sapiens.
- Length: 326 amino acids.
- Top disease associations (Open Targets): high density lipoprotein cholesterol measurement, erythrocyte count and cardiac arrhythmia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Olfactory receptor 4C5 |
|---|---|
| UniProt accession | Q8NGB2 |
| Gene | OR4C5 |
| Organism | Homo sapiens |
| Length | 326 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (20)
Diseases linked to this target (Open Targets).
- high density lipoprotein cholesterol measurement · score 0.08
- erythrocyte count · score 0.07
- cardiac arrhythmia · score 0.06
- chronic obstructive pulmonary disease · score 0.05
- diastolic blood pressure · score 0.04
- self reported educational attainment · score 0.04
- apolipoprotein A 1 measurement · score 0.03
- parental genotype effect measurement · score 0.03
- birth weight · score 0.03
- loneliness measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NGB2-F1 | alphafold | PREDICTED | 86.17 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NGB2.
Amino-acid sequence (326 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OR4C5?
The strongest Open Targets associations for OR4C5 are high density lipoprotein cholesterol measurement, erythrocyte count, cardiac arrhythmia, chronic obstructive pulmonary disease and diastolic blood pressure.
How long is the OR4C5 protein?
The Homo sapiens OR4C5 protein (UniProt Q8NGB2) is 326 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NGB2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NGB2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.