Olfactory receptor 4S1 (OR4S1)
Homo sapiens — UniProt Q8NGB4
Data last refreshed: (UniProt release unknown)
Key facts
Olfactory receptor 4S1 (OR4S1) is a protein from Homo sapiens identified by UniProt accession Q8NGB4, 309 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.
- UniProt accession: Q8NGB4; gene symbol OR4S1.
- Organism: Homo sapiens.
- Length: 309 amino acids.
- Top disease associations (Open Targets): low grade glioma, prostate adenocarcinoma and ovarian cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Olfactory receptor 4S1 |
|---|---|
| UniProt accession | Q8NGB4 |
| Gene | OR4S1 |
| Organism | Homo sapiens |
| Length | 309 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (22)
Diseases linked to this target (Open Targets).
- low grade glioma · score 0.18
- prostate adenocarcinoma · score 0.18
- ovarian cancer · score 0.18
- breast adenocarcinoma · score 0.18
- glomerular filtration rate · score 0.13
- cardiac arrhythmia · score 0.05
- chronic obstructive pulmonary disease · score 0.04
- platelet component distribution width · score 0.04
- erythrocyte count · score 0.04
- IGF-1 measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NGB4-F1 | alphafold | PREDICTED | 88.84 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NGB4.
Amino-acid sequence (309 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OR4S1?
The strongest Open Targets associations for OR4S1 are low grade glioma, prostate adenocarcinoma, ovarian cancer, breast adenocarcinoma and glomerular filtration rate.
How long is the OR4S1 protein?
The Homo sapiens OR4S1 protein (UniProt Q8NGB4) is 309 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NGB4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NGB4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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