Olfactory receptor 4F15 (OR4F15)
Homo sapiens — UniProt Q8NGB8
Data last refreshed: (UniProt release unknown)
Key facts
Olfactory receptor 4F15 (OR4F15) is a protein from Homo sapiens identified by UniProt accession Q8NGB8, 312 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.
- UniProt accession: Q8NGB8; gene symbol OR4F15.
- Organism: Homo sapiens.
- Length: 312 amino acids.
- Top disease associations (Open Targets): clear cell renal carcinoma, breast adenocarcinoma and ulcerative colitis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Olfactory receptor 4F15 |
|---|---|
| UniProt accession | Q8NGB8 |
| Gene | OR4F15 |
| Organism | Homo sapiens |
| Length | 312 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (5)
Diseases linked to this target (Open Targets).
- clear cell renal carcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- ulcerative colitis · score 0.08
- salivary gland carcinoma · score 0.00
- cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NGB8-F1 | alphafold | PREDICTED | 88.06 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NGB8.
Amino-acid sequence (312 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OR4F15?
The strongest Open Targets associations for OR4F15 are clear cell renal carcinoma, breast adenocarcinoma, ulcerative colitis, salivary gland carcinoma and cancer.
How long is the OR4F15 protein?
The Homo sapiens OR4F15 protein (UniProt Q8NGB8) is 312 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NGB8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NGB8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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