Olfactory receptor 4F6 (OR4F6)
Homo sapiens — UniProt Q8NGB9
Data last refreshed: (UniProt release unknown)
Key facts
Olfactory receptor 4F6 (OR4F6) is a protein from Homo sapiens identified by UniProt accession Q8NGB9, 312 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.
- UniProt accession: Q8NGB9; gene symbol OR4F6.
- Organism: Homo sapiens.
- Length: 312 amino acids.
- Top disease associations (Open Targets): chronic lymphocytic leukemia, hepatocellular carcinoma and clear cell renal carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Olfactory receptor 4F6 |
|---|---|
| UniProt accession | Q8NGB9 |
| Gene | OR4F6 |
| Organism | Homo sapiens |
| Length | 312 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (13)
Diseases linked to this target (Open Targets).
- chronic lymphocytic leukemia · score 0.18
- hepatocellular carcinoma · score 0.18
- clear cell renal carcinoma · score 0.18
- prostate adenocarcinoma · score 0.18
- pancreatic adenocarcinoma · score 0.18
- ovarian cancer · score 0.18
- low grade glioma · score 0.18
- breast adenocarcinoma · score 0.18
- ulcerative colitis · score 0.06
- metabolic syndrome · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NGB9-F1 | alphafold | PREDICTED | 87.52 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NGB9.
Amino-acid sequence (312 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OR4F6?
The strongest Open Targets associations for OR4F6 are chronic lymphocytic leukemia, hepatocellular carcinoma, clear cell renal carcinoma, prostate adenocarcinoma and pancreatic adenocarcinoma.
How long is the OR4F6 protein?
The Homo sapiens OR4F6 protein (UniProt Q8NGB9) is 312 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NGB9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NGB9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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