Olfactory receptor 4K14 (OR4K14)
Homo sapiens — UniProt Q8NGD5
Data last refreshed: (UniProt release unknown)
Key facts
Olfactory receptor 4K14 (OR4K14) is a protein from Homo sapiens identified by UniProt accession Q8NGD5, 310 residues long. MolForge cross-references it against 0 known binders and 3 disease associations.
- UniProt accession: Q8NGD5; gene symbol OR4K14.
- Organism: Homo sapiens.
- Length: 310 amino acids.
- Top disease associations (Open Targets): prostate adenocarcinoma, breast adenocarcinoma and open-angle glaucoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Olfactory receptor 4K14 |
|---|---|
| UniProt accession | Q8NGD5 |
| Gene | OR4K14 |
| Organism | Homo sapiens |
| Length | 310 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (3)
Diseases linked to this target (Open Targets).
- prostate adenocarcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- open-angle glaucoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NGD5-F1 | alphafold | PREDICTED | 85.92 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NGD5.
Amino-acid sequence (310 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OR4K14?
The strongest Open Targets associations for OR4K14 are prostate adenocarcinoma, breast adenocarcinoma and open-angle glaucoma.
How long is the OR4K14 protein?
The Homo sapiens OR4K14 protein (UniProt Q8NGD5) is 310 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NGD5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NGD5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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