Olfactory receptor 10AD1 (OR10AD1)

About Olfactory receptor 10AD1

Olfactory receptor 10AD1 (OR10AD1) is a protein from Homo sapiens identified by UniProt accession Q8NGE0, 317 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.

Target properties

Protein name	Olfactory receptor 10AD1
UniProt accession	Q8NGE0
Gene	OR10AD1
Organism	Homo sapiens
Length	317 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (25)

Diseases linked to this target (Open Targets).

hemoglobin measurement · score 0.28
erythrocyte count · score 0.27
hypertension · score 0.22
cardiovascular disease · score 0.20
ovarian cancer · score 0.18
clear cell renal carcinoma · score 0.18
HbA1c measurement · score 0.17
systolic blood pressure · score 0.17
blood pressure · score 0.17
platelet count · score 0.12

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NGE0-F1	alphafold	PREDICTED	80.36	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NGE0.

Amino-acid sequence (317 residues)

MLRNGSIVTE FILVGFQQSS TSTRALLFAL FLALYSLTMA MNGLIIFITS WTDPKLNSPM YFFLGHLSLL DVCFITTTIP QMLIHLVVRD HIVSFVCCMT QMYFVFCVGV AECILLAFMA YDRYVAICYP LNYVPIISQK VCVRLVGTAW FFGLINGIFL EYISFREPFR RDNHIESFFC EAPIVIGLSC GDPQFSLWAI FADAIVVILS PMVLTVTSYV HILATILSKA SSSGRGKTFS TCASHLTVVI FLYTSAMFSY MNPHSTHGPD KDKPFSLLYT IITPMCNPII YSFRNKEIKE AMVRALGRTR LAQPQSV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards