About Olfactory receptor 4D9
Olfactory receptor 4D9 (OR4D9) is a protein
from Homo sapiens identified by UniProt accession
Q8NGE8, 314 residues long.
MolForge cross-references it against 0 known binders and
9 disease associations.
Target properties
| Protein name | Olfactory receptor 4D9 |
|---|
| UniProt accession | Q8NGE8 |
|---|
| Gene | OR4D9 |
|---|
| Organism | Homo sapiens |
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| Length | 314 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (9)
Diseases linked to this target (Open Targets).
- thyroid gland adenocarcinoma · score 0.22
- prostate adenocarcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- body height · score 0.05
- colorectal adenocarcinoma · score 0.04
- protein measurement · score 0.02
- breast carcinoma · score 0.02
- glioblastoma multiforme · score 0.01
- psoriasis · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q8NGE8-F1 | alphafold | PREDICTED | 88.71 | — |
Amino-acid sequence (314 residues)
MDQRNYTRVK EFTFLGITQS RELSQVLFTF LFLVYMTTLM GNFLIMVTVT CESHLHTPMY FLLRNLSILD ICFSSITAPK VLIDLLSETK TISFSGCVTQ MFFFHLLGGA DVFSLSVMAF DRYIAISKPL HYMTIMSRGR CTGLIVASWV GGFVHSIAQI SLLLPLPFCG PNVLDTFYCD VPQVLKLACT DTFTLELLMI SNNGLVSWFV FFFLLISYTV ILMMLRSHTG EGRRKAISTC TSHITVVTLH FVPCIYVYAR PFTALPTDTA ISVTFTVISP LLNPIIYTLR NQEMKLAMRK LKRRLGQSER ILIQ
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