Olfactory receptor 8J3 (OR8J3)
Homo sapiens — UniProt Q8NGG0
Data last refreshed: (UniProt release unknown)
Key facts
Olfactory receptor 8J3 (OR8J3) is a protein from Homo sapiens identified by UniProt accession Q8NGG0, 315 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.
- UniProt accession: Q8NGG0; gene symbol OR8J3.
- Organism: Homo sapiens.
- Length: 315 amino acids.
- Top disease associations (Open Targets): apolipoprotein A 1 measurement, chronic lymphocytic leukemia and clear cell renal carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Olfactory receptor 8J3 |
|---|---|
| UniProt accession | Q8NGG0 |
| Gene | OR8J3 |
| Organism | Homo sapiens |
| Length | 315 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (12)
Diseases linked to this target (Open Targets).
- apolipoprotein A 1 measurement · score 0.24
- chronic lymphocytic leukemia · score 0.18
- clear cell renal carcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- IGF-1 measurement · score 0.09
- cystatin C measurement · score 0.09
- leukocyte count · score 0.07
- C-reactive protein measurement · score 0.05
- high density lipoprotein cholesterol measurement · score 0.04
- diastolic blood pressure · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NGG0-F1 | alphafold | PREDICTED | 89.60 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NGG0.
Amino-acid sequence (315 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OR8J3?
The strongest Open Targets associations for OR8J3 are apolipoprotein A 1 measurement, chronic lymphocytic leukemia, clear cell renal carcinoma, breast adenocarcinoma and IGF-1 measurement.
How long is the OR8J3 protein?
The Homo sapiens OR8J3 protein (UniProt Q8NGG0) is 315 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NGG0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NGG0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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