Olfactory receptor 8B12 (OR8B12)

About Olfactory receptor 8B12

Olfactory receptor 8B12 (OR8B12) is a protein from Homo sapiens identified by UniProt accession Q8NGG6, 310 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.

Target properties

Protein name	Olfactory receptor 8B12
UniProt accession	Q8NGG6
Gene	OR8B12
Organism	Homo sapiens
Length	310 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (5)

Diseases linked to this target (Open Targets).

medulloblastoma · score 0.21
clear cell renal carcinoma · score 0.18
ovarian cancer · score 0.18
breast adenocarcinoma · score 0.18
acute myeloid leukemia · score 0.14

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NGG6-F1	alphafold	PREDICTED	88.78	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NGG6.

Amino-acid sequence (310 residues)

MAAKNSSVTE FILEGLTHQP GLRIPLFFLF LGFYTVTVVG NLGLITLIGL NSHLHTPMYF FLFNLSLIDF CFSTTITPKM LMSFVSRKNI ISFTGCMTQL FFFCFFVVSE SFILSAMAYD RYVAICNPLL YTVTMSCQVC LLLLLGAYGM GFAGAMAHTG SIMNLTFCAD NLVNHFMCDI LPLLELSCNS SYMNELVVFI VVAVDVGMPI VTVFISYALI LSSILHNSST EGRSKAFSTC SSHIIVVSLF FGSGAFMYLK PLSILPLEQG KVSSLFYTII VPVLNPLIYS LRNKDVKVAL RRTLGRKIFS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards