Olfactory receptor 8B3 (OR8B3)

About Olfactory receptor 8B3

Olfactory receptor 8B3 (OR8B3) is a protein from Homo sapiens identified by UniProt accession Q8NGG8, 313 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.

Target properties

Protein name	Olfactory receptor 8B3
UniProt accession	Q8NGG8
Gene	OR8B3
Organism	Homo sapiens
Length	313 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (4)

Diseases linked to this target (Open Targets).

clear cell renal carcinoma · score 0.18
ovarian cancer · score 0.18
breast adenocarcinoma · score 0.18
Alzheimer disease · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NGG8-F1	alphafold	PREDICTED	90.79	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NGG8.

Amino-acid sequence (313 residues)

MLARNNSLVT EFILAGLTDH PEFQQPLFFL FLVVYIVTMV GNLGLIILFG LNSHLHTPMY YFLFNLSFID LCYSSVFTPK MLMNFVSKKN IISYVGCMTQ LFFFLFFVIS ECYMLTSMAY DRYVAICNPL LYKVTMSHQV CSMLTFAAYI MGLAGATAHT GCMLRLTFCS ANIINHYLCD ILPLLQLSCT STYVNEVVVL IVVGINIMVP SCTILISYVF IVTSILHIKS TQGRSKAFST CSSHVIALSL FFGSAAFMYI KYSSGSMEQG KVSSVFYTNV VPMLNPLIYS LRNKDVKVAL RKALIKIQRR NIF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards