Olfactory receptor 52L1 (OR52L1)

About Olfactory receptor 52L1

Olfactory receptor 52L1 (OR52L1) is a protein from Homo sapiens identified by UniProt accession Q8NGH7, 329 residues long. MolForge cross-references it against 0 known binders and 6 disease associations.

Target properties

Protein name	Olfactory receptor 52L1
UniProt accession	Q8NGH7
Gene	OR52L1
Organism	Homo sapiens
Length	329 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (6)

Diseases linked to this target (Open Targets).

medulloblastoma · score 0.21
clear cell renal carcinoma · score 0.18
pancreatic adenocarcinoma · score 0.18
breast adenocarcinoma · score 0.18
pseudobulbar palsy · score 0.01
retinitis pigmentosa · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NGH7-F1	alphafold	PREDICTED	85.27	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NGH7.

Amino-acid sequence (329 residues)

MTLVSFFSFL SKPLIMLLSN SSWRLSQPSF LLVGIPGLEE SQHWIALPLG ILYLLALVGN VTILFIIWMD PSLHQSMYLF LSMLAAIDLV LASSTAPKAL AVLLVHAHEI GYIVCLIQMF FIHAFSSMES GVLVAMALDR YVAICHPLHH STILHPGVIG RIGMVVLVRG LLLLIPFPIL LGTLIFCQAT IIGHAYCEHM AVVKLACSET TVNRAYGLTM ALLVIGLDVL AIGVSYAHIL QAVLKVPGSE ARLKAFSTCG SHICVILVFY VPGIFSFLTH RFGHHVPHHV HVLLATRYLL MPPALNPLVY GVKTQQIRQR VLRVFTQKD

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards