Olfactory receptor 52E4 (OR52E4)
Homo sapiens — UniProt Q8NGH9
Data last refreshed: (UniProt release unknown)
Key facts
Olfactory receptor 52E4 (OR52E4) is a protein from Homo sapiens identified by UniProt accession Q8NGH9, 312 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.
- UniProt accession: Q8NGH9; gene symbol OR52E4.
- Organism: Homo sapiens.
- Length: 312 amino acids.
- Top disease associations (Open Targets): neuroblastoma, hepatocellular carcinoma and clear cell renal carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Olfactory receptor 52E4 |
|---|---|
| UniProt accession | Q8NGH9 |
| Gene | OR52E4 |
| Organism | Homo sapiens |
| Length | 312 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (18)
Diseases linked to this target (Open Targets).
- neuroblastoma · score 0.21
- hepatocellular carcinoma · score 0.18
- clear cell renal carcinoma · score 0.18
- prostate adenocarcinoma · score 0.18
- ovarian cancer · score 0.18
- low grade glioma · score 0.18
- breast adenocarcinoma · score 0.18
- platelet count · score 0.16
- coronary artery disease · score 0.14
- myocardial infarction · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NGH9-F1 | alphafold | PREDICTED | 89.02 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NGH9.
Amino-acid sequence (312 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OR52E4?
The strongest Open Targets associations for OR52E4 are neuroblastoma, hepatocellular carcinoma, clear cell renal carcinoma, prostate adenocarcinoma and ovarian cancer.
How long is the OR52E4 protein?
The Homo sapiens OR52E4 protein (UniProt Q8NGH9) is 312 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NGH9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NGH9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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