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Olfactory receptor 4D10 (OR4D10)

Homo sapiens — UniProt Q8NGI6

Gene: OR4D10Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Olfactory receptor 4D10 (OR4D10) is a protein from Homo sapiens identified by UniProt accession Q8NGI6, 311 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.

  • UniProt accession: Q8NGI6; gene symbol OR4D10.
  • Organism: Homo sapiens.
  • Length: 311 amino acids.
  • Top disease associations (Open Targets): prostate adenocarcinoma, clear cell renal carcinoma and low grade glioma.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameOlfactory receptor 4D10
UniProt accessionQ8NGI6
GeneOR4D10
OrganismHomo sapiens
Length311 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (10)

Diseases linked to this target (Open Targets).

  • prostate adenocarcinoma · score 0.18
  • clear cell renal carcinoma · score 0.18
  • low grade glioma · score 0.18
  • ovarian cancer · score 0.18
  • breast adenocarcinoma · score 0.18
  • body height · score 0.03
  • smoking behavior · score 0.02
  • Obesity · score 0.01
  • papillary thyroid carcinoma · score 0.00
  • diabetes mellitus · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8NGI6-F1alphafoldPREDICTED90.14—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NGI6.

Amino-acid sequence (311 residues)

MEMENCTRVK EFIFLGLTQN REVSLVLFLF LLLVYVTTLL GNLLIMVTVT CESRLHTPMY FLLHNLSIAD ICFSSITVPK VLVDLLSERK TISFNHCFTQ MFLFHLIGGV DVFSLSVMAL DRYVAISKPL HYATIMSRDH CIGLTVAAWL GGFVHSIVQI SLLLPLPFCG PNVLDTFYCD VHRVLKLAHT DIFILELLMI SNNGLLTTLW FFLLLVSYIV ILSLPKSQAG EGRRKAISTC TSHITVVTLH FVPCIYVYAR PFTALPMDKA ISVTFTVISP LLNPLIYTLR NHEMKSAMRR LKRRLVPSDR K

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with OR4D10?

The strongest Open Targets associations for OR4D10 are prostate adenocarcinoma, clear cell renal carcinoma, low grade glioma, ovarian cancer and breast adenocarcinoma.

How long is the OR4D10 protein?

The Homo sapiens OR4D10 protein (UniProt Q8NGI6) is 311 amino acids long.

Browse: Targets: O · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ8NGI6
GeneOR4D10
OrganismHomo sapiens
Length311
Binders0
Diseases10
View on UniProt