Olfactory receptor 5AN1 (OR5AN1)
Homo sapiens — UniProt Q8NGI8
Data last refreshed: (UniProt release unknown)
Key facts
Olfactory receptor 5AN1 (OR5AN1) is a protein from Homo sapiens identified by UniProt accession Q8NGI8, 311 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.
- UniProt accession: Q8NGI8; gene symbol OR5AN1.
- Organism: Homo sapiens.
- Length: 311 amino acids.
- Top disease associations (Open Targets): ovarian cancer, low grade glioma and breast adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Olfactory receptor 5AN1 |
|---|---|
| UniProt accession | Q8NGI8 |
| Gene | OR5AN1 |
| Organism | Homo sapiens |
| Length | 311 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (9)
Diseases linked to this target (Open Targets).
- ovarian cancer · score 0.18
- low grade glioma · score 0.18
- breast adenocarcinoma · score 0.18
- multiple myeloma · score 0.16
- 3-hydroxypropylmercapturic acid measurement · score 0.16
- body height · score 0.09
- smoking behavior · score 0.03
- breast carcinoma · score 0.02
- papillary thyroid carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NGI8-F1 | alphafold | PREDICTED | 89.12 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NGI8.
Amino-acid sequence (311 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OR5AN1?
The strongest Open Targets associations for OR5AN1 are ovarian cancer, low grade glioma, breast adenocarcinoma, multiple myeloma and 3-hydroxypropylmercapturic acid measurement.
How long is the OR5AN1 protein?
The Homo sapiens OR5AN1 protein (UniProt Q8NGI8) is 311 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NGI8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NGI8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.