Olfactory receptor 4D6 (OR4D6)
Homo sapiens — UniProt Q8NGJ1
Data last refreshed: (UniProt release unknown)
Key facts
Olfactory receptor 4D6 (OR4D6) is a protein from Homo sapiens identified by UniProt accession Q8NGJ1, 314 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.
- UniProt accession: Q8NGJ1; gene symbol OR4D6.
- Organism: Homo sapiens.
- Length: 314 amino acids.
- Top disease associations (Open Targets): neuroblastoma, medulloblastoma and smoking behavior.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Olfactory receptor 4D6 |
|---|---|
| UniProt accession | Q8NGJ1 |
| Gene | OR4D6 |
| Organism | Homo sapiens |
| Length | 314 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (11)
Diseases linked to this target (Open Targets).
- neuroblastoma · score 0.21
- medulloblastoma · score 0.21
- smoking behavior · score 0.21
- ovarian cancer · score 0.18
- prostate adenocarcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- smoking status measurement · score 0.13
- sensory perception of smell · score 0.04
- body height · score 0.03
- cancer · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NGJ1-F1 | alphafold | PREDICTED | 88.53 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NGJ1.
Amino-acid sequence (314 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OR4D6?
The strongest Open Targets associations for OR4D6 are neuroblastoma, medulloblastoma, smoking behavior, ovarian cancer and prostate adenocarcinoma.
How long is the OR4D6 protein?
The Homo sapiens OR4D6 protein (UniProt Q8NGJ1) is 314 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NGJ1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NGJ1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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