Olfactory receptor 52E2 (OR52E2)
Homo sapiens — UniProt Q8NGJ4
Data last refreshed: (UniProt release unknown)
Key facts
Olfactory receptor 52E2 (OR52E2) is a protein from Homo sapiens identified by UniProt accession Q8NGJ4, 325 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.
- UniProt accession: Q8NGJ4; gene symbol OR52E2.
- Organism: Homo sapiens.
- Length: 325 amino acids.
- Top disease associations (Open Targets): neuroblastoma, medulloblastoma and prostate adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Olfactory receptor 52E2 |
|---|---|
| UniProt accession | Q8NGJ4 |
| Gene | OR52E2 |
| Organism | Homo sapiens |
| Length | 325 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (7)
Diseases linked to this target (Open Targets).
- neuroblastoma · score 0.21
- medulloblastoma · score 0.21
- prostate adenocarcinoma · score 0.18
- ovarian cancer · score 0.18
- breast adenocarcinoma · score 0.18
- diet measurement · score 0.11
- sickle cell anemia · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NGJ4-F1 | alphafold | PREDICTED | 86.26 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NGJ4.
Amino-acid sequence (325 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OR52E2?
The strongest Open Targets associations for OR52E2 are neuroblastoma, medulloblastoma, prostate adenocarcinoma, ovarian cancer and breast adenocarcinoma.
How long is the OR52E2 protein?
The Homo sapiens OR52E2 protein (UniProt Q8NGJ4) is 325 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NGJ4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NGJ4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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