Olfactory receptor 51A4 (OR51A4)
Homo sapiens — UniProt Q8NGJ6
Data last refreshed: (UniProt release unknown)
Key facts
Olfactory receptor 51A4 (OR51A4) is a protein from Homo sapiens identified by UniProt accession Q8NGJ6, 313 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.
- UniProt accession: Q8NGJ6; gene symbol OR51A4.
- Organism: Homo sapiens.
- Length: 313 amino acids.
- Top disease associations (Open Targets): low grade glioma, ovarian cancer and breast adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Olfactory receptor 51A4 |
|---|---|
| UniProt accession | Q8NGJ6 |
| Gene | OR51A4 |
| Organism | Homo sapiens |
| Length | 313 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (7)
Diseases linked to this target (Open Targets).
- low grade glioma · score 0.18
- ovarian cancer · score 0.18
- breast adenocarcinoma · score 0.18
- DNA methylation · score 0.11
- prostate carcinoma · score 0.02
- diabetes mellitus · score 0.00
- cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NGJ6-F1 | alphafold | PREDICTED | 88.91 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NGJ6.
Amino-acid sequence (313 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OR51A4?
The strongest Open Targets associations for OR51A4 are low grade glioma, ovarian cancer, breast adenocarcinoma, DNA methylation and prostate carcinoma.
How long is the OR51A4 protein?
The Homo sapiens OR51A4 protein (UniProt Q8NGJ6) is 313 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NGJ6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NGJ6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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