Olfactory receptor 52I1 (OR52I1)

About Olfactory receptor 52I1

Olfactory receptor 52I1 (OR52I1) is a protein from Homo sapiens identified by UniProt accession Q8NGK6, 324 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.

Target properties

Protein name	Olfactory receptor 52I1
UniProt accession	Q8NGK6
Gene	OR52I1
Organism	Homo sapiens
Length	324 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (7)

Diseases linked to this target (Open Targets).

monocyte count · score 0.36
monocyte percentage of leukocytes · score 0.26
medulloblastoma · score 0.21
breast adenocarcinoma · score 0.18
PHF-tau measurement · score 0.08
pancreatic adenocarcinoma · score 0.04
non-small cell lung carcinoma · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NGK6-F1	alphafold	PREDICTED	85.47	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NGK6.

Amino-acid sequence (324 residues)

MLGPAYNHTM ETPASFLLVG IPGLQSSHLW LAISLSAMYI TALLGNTLIV TAIWMDSTRH EPMYCFLCVL AAVDIVMASS VVPKMVSIFC SGDSSISFSA CFTQMFFVHL ATAVETGLLL TMAFDRYVAI CKPLHYKRIL TPQVMLGMSM AVTIRAVTFM TPLSWMMNHL PFCGSNVVVH SYCKHIALAR LACADPVPSS LYSLIGSSLM VGSDVAFIAA SYILILRAVF DLSSKTAQLK ALSTCGSHVG VMALYYLPGM ASIYAAWLGQ DIVPLHTQVL LADLYVIIPA TLNPIIYGMR TKQLLEGIWS YLMHFLFDHS NLGS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards