Olfactory receptor 4D5 (OR4D5)
Homo sapiens — UniProt Q8NGN0
Data last refreshed: (UniProt release unknown)
Key facts
Olfactory receptor 4D5 (OR4D5) is a protein from Homo sapiens identified by UniProt accession Q8NGN0, 318 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.
- UniProt accession: Q8NGN0; gene symbol OR4D5.
- Organism: Homo sapiens.
- Length: 318 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, thyroid gland adenocarcinoma and pancreatic adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Olfactory receptor 4D5 |
|---|---|
| UniProt accession | Q8NGN0 |
| Gene | OR4D5 |
| Organism | Homo sapiens |
| Length | 318 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (10)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.32
- thyroid gland adenocarcinoma · score 0.22
- pancreatic adenocarcinoma · score 0.18
- prostate adenocarcinoma · score 0.18
- ovarian cancer · score 0.18
- colorectal adenocarcinoma · score 0.04
- breast carcinoma · score 0.04
- urate measurement · score 0.03
- bone density · score 0.03
- gastric carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NGN0-F1 | alphafold | PREDICTED | 86.99 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NGN0.
Amino-acid sequence (318 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OR4D5?
The strongest Open Targets associations for OR4D5 are neurodegenerative disease, thyroid gland adenocarcinoma, pancreatic adenocarcinoma, prostate adenocarcinoma and ovarian cancer.
How long is the OR4D5 protein?
The Homo sapiens OR4D5 protein (UniProt Q8NGN0) is 318 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NGN0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NGN0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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