Olfactory receptor 5M8 (OR5M8)
Homo sapiens — UniProt Q8NGP6
Data last refreshed: (UniProt release unknown)
Key facts
Olfactory receptor 5M8 (OR5M8) is a protein from Homo sapiens identified by UniProt accession Q8NGP6, 311 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.
- UniProt accession: Q8NGP6; gene symbol OR5M8.
- Organism: Homo sapiens.
- Length: 311 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, neuroblastoma and clear cell renal carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Olfactory receptor 5M8 |
|---|---|
| UniProt accession | Q8NGP6 |
| Gene | OR5M8 |
| Organism | Homo sapiens |
| Length | 311 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (17)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.23
- neuroblastoma · score 0.21
- clear cell renal carcinoma · score 0.18
- low grade glioma · score 0.18
- hepatocellular carcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- hypertension · score 0.05
- blood pressure · score 0.05
- coffee consumption measurement · score 0.03
- unipolar depression · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NGP6-F1 | alphafold | PREDICTED | 90.04 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NGP6.
Amino-acid sequence (311 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OR5M8?
The strongest Open Targets associations for OR5M8 are neurodegenerative disease, neuroblastoma, clear cell renal carcinoma, low grade glioma and hepatocellular carcinoma.
How long is the OR5M8 protein?
The Homo sapiens OR5M8 protein (UniProt Q8NGP6) is 311 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NGP6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NGP6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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