Olfactory receptor 1K1 (OR1K1)
Homo sapiens — UniProt Q8NGR3
Data last refreshed: (UniProt release unknown)
Key facts
Olfactory receptor 1K1 (OR1K1) is a protein from Homo sapiens identified by UniProt accession Q8NGR3, 316 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.
- UniProt accession: Q8NGR3; gene symbol OR1K1.
- Organism: Homo sapiens.
- Length: 316 amino acids.
- Top disease associations (Open Targets): medulloblastoma, ovarian cancer and prostate adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Olfactory receptor 1K1 |
|---|---|
| UniProt accession | Q8NGR3 |
| Gene | OR1K1 |
| Organism | Homo sapiens |
| Length | 316 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (9)
Diseases linked to this target (Open Targets).
- medulloblastoma · score 0.21
- ovarian cancer · score 0.18
- prostate adenocarcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- lymphocyte percentage of leukocytes · score 0.02
- bone density · score 0.02
- gut microbiome measurement · score 0.02
- measles · score 0.00
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NGR3-F1 | alphafold | PREDICTED | 85.47 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NGR3.
Amino-acid sequence (316 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OR1K1?
The strongest Open Targets associations for OR1K1 are medulloblastoma, ovarian cancer, prostate adenocarcinoma, breast adenocarcinoma and lymphocyte percentage of leukocytes.
How long is the OR1K1 protein?
The Homo sapiens OR1K1 protein (UniProt Q8NGR3) is 316 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NGR3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NGR3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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