Olfactory receptor 1K1 (OR1K1)

About Olfactory receptor 1K1

Olfactory receptor 1K1 (OR1K1) is a protein from Homo sapiens identified by UniProt accession Q8NGR3, 316 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.

Target properties

Protein name	Olfactory receptor 1K1
UniProt accession	Q8NGR3
Gene	OR1K1
Organism	Homo sapiens
Length	316 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (9)

Diseases linked to this target (Open Targets).

medulloblastoma · score 0.21
ovarian cancer · score 0.18
prostate adenocarcinoma · score 0.18
breast adenocarcinoma · score 0.18
lymphocyte percentage of leukocytes · score 0.02
bone density · score 0.02
gut microbiome measurement · score 0.02
measles · score 0.00
neoplasm · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8NGR3-F1	alphafold	PREDICTED	85.47	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NGR3.

Amino-acid sequence (316 residues)

MEAANESSEG ISFVLLGLTT SPGQQRPLFV LFLLLYVASL LGNGLIVAAI QASPALHAPM YFLLAHLSFA DLCFASVTVP KMLANLLAHD HSISLAGCLT QMYFFFALGV TDSCLLAAMA YDCYVAIRHP LPYATRMSRA MCAALVGMAW LVSHVHSLLY ILLMARLSFC ASHQVPHFFC DHQPLLRLSC SDTHHIQLLI FTEGAAVVVT PFLLILASYG AIAAAVLQLP SASGRLRAVS TCGSHLAVVS LFYGTVIAVY FQATSRREAE WGRVATVMYT VVTPMLNPII YSLWNRDVQG ALRALLIGRR ISASDS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards