Olfactory receptor 1J2 (OR1J2)
Homo sapiens — UniProt Q8NGS2
Data last refreshed: (UniProt release unknown)
Key facts
Olfactory receptor 1J2 (OR1J2) is a protein from Homo sapiens identified by UniProt accession Q8NGS2, 313 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.
- UniProt accession: Q8NGS2; gene symbol OR1J2.
- Organism: Homo sapiens.
- Length: 313 amino acids.
- Top disease associations (Open Targets): thyroid gland adenocarcinoma, pancreatic adenocarcinoma and clear cell renal carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Olfactory receptor 1J2 |
|---|---|
| UniProt accession | Q8NGS2 |
| Gene | OR1J2 |
| Organism | Homo sapiens |
| Length | 313 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (12)
Diseases linked to this target (Open Targets).
- thyroid gland adenocarcinoma · score 0.22
- pancreatic adenocarcinoma · score 0.18
- clear cell renal carcinoma · score 0.18
- breast adenocarcinoma · score 0.18
- acute myeloid leukemia · score 0.14
- lymphocyte percentage of leukocytes · score 0.03
- Miyoshi myopathy · score 0.00
- neoplasm · score 0.00
- cancer · score 0.00
- arthrogryposis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8NGS2-F1 | alphafold | PREDICTED | 88.16 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8NGS2.
Amino-acid sequence (313 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OR1J2?
The strongest Open Targets associations for OR1J2 are thyroid gland adenocarcinoma, pancreatic adenocarcinoma, clear cell renal carcinoma, breast adenocarcinoma and acute myeloid leukemia.
How long is the OR1J2 protein?
The Homo sapiens OR1J2 protein (UniProt Q8NGS2) is 313 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8NGS2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8NGS2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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